Linda Nicholson

Linda Nicholson is a Professor in the Department of Molecular Biology and Genetics at Cornell University, and the Hays and James M. Clark Director of the Office of Undergraduate Biology. Her research focuses on protein dynamics and function using NMR spectroscopy, with applications to diseases like Alzheimer’s and asthma. She has pioneered studies on proline isomerization switches and the coupling of innate immunity signaling to actin cytoskeleton regulation.

Education: While specific academic degrees are not detailed in the provided text, Nicholson joined Cornell’s faculty in 1994, indicating advanced training in molecular biology or related fields.

Research Interests: Nicholson’s work integrates biophysics, structural biology, and disease mechanisms. Key areas include protein dynamics in disease contexts (e.g., Src proto-oncoprotein, Lyme disease proteins), and the thermodynamics of protein interactions. Her lab explores how ligand binding propagates through protein structures, informing therapeutic strategies.

Awards & Recognition: Nicholson has received multiple accolades, including the 2023 Faculty Award for Excellence in Research, Teaching, and Service through Diversity. Her advising and mentorship efforts, particularly with underrepresented students via the Posse Foundation, have been widely recognized.

Scholarly Impact: Over 30+ publications span protein structure-function relationships, antimicrobial peptides, and signaling pathways. Her work bridges basic science and translational research, with implications for drug discovery and immune modulation.

Leadership: As Director of Undergraduate Biology, Nicholson oversees curriculum development and student support. She chairs diversity initiatives and collaborates across disciplines to enhance inclusive excellence in STEM education.