Liangyou Rui

Liangyou Rui is a Professor at the University of Michigan, holding joint appointments in the Medical School and the Department of Molecular and Integrative Physiology. They are also the Louis G D'Alecy Collegiate Professor, a distinguished named chair, and participate in mentoring students and researchers.

• Education: PhD from the University of Michigan Medical School
• Postdoctoral Training: Harvard Medical School and Joslin Diabetes Center

Rui's research focuses on the molecular and epigenetic mechanisms underlying metabolic disorders. Key areas include:

• Epigenetic and epitranscriptomic regulation
• Obesity and related metabolic dysfunctions
• Type 2 Diabetes and NASH
• RNA methylation (e.g., m6A) and its impact on metabolic pathways
• Hepatic glucose production and lipid metabolism
• Neuronal signaling in energy balance
• Inflammation and immune-metabolic crosstalk

Rui's recent publications highlight interdisciplinary work bridging molecular biology, endocrinology, and oncology, with a focus on:

• Non-canonical NFκB signaling in metabolic tissues
• Role of NIK in tumor-brown adipose crosstalk
• Epigenetic regulators like Slug in adipogenesis
• RNA methylation's influence on hypothalamic control of metabolism

Awards and recognitions include the prestigious Louis G D'Alecy Collegiate Professor chair, reflecting their leadership in metabolic research.

Rui collaborates with multidisciplinary centers at the University of Michigan, including:

• Caswell Diabetes Institute
• Rogel Cancer Center
• Global REACH
• Center for Cell Plasticity and Organ Design
• Biosciences Initiative

Their work is further disseminated through the Liangyou Rui Lab, which explores epigenetic mechanisms in metabolic diseases.