Carey N. Lumeng

Dr. Carey N. Lumeng is the Frederick G.L. Huetwell Professor for the Cure and Prevention of Birth Defects, Professor of Pediatrics, and Professor of Molecular and Integrative Physiology at the University of Michigan Medical School. He serves as Director of the Division of Pediatric Pulmonary Medicine, Associate Director of the Michigan Medical Scientist Training Program (MSTP), and holds memberships in the Graduate Program in Immunology and Cellular & Molecular Biology Graduate Program. His research laboratory is located at 2057 Biomedical Sciences Research Building in Ann Arbor.

Education:

• A.B. in Molecular Biology, Princeton University
• M.D. and Ph.D. in Human Genetics, University of Michigan MSTP Program
• Pediatrics Residency, Boston Combined Residency Program (Boston Children's Hospital/Boston Medical Center)
• Pediatric Pulmonology Fellowship, University of Michigan

Research Focus: Dr. Lumeng leads a NIH-funded program investigating immunometabolic mechanisms linking obesity to metabolic diseases. His laboratory studies adipose tissue immune networks, focusing on macrophage polarization, T-cell dysfunction, and cellular crosstalk in obesity using single-cell genomics, murine models, and human tissue collaborations with bariatric surgeons. Key areas include:

• Inflammation-driven insulin resistance
• Adipose tissue macrophage proliferation
• Antigen-presenting cell functions
• Genetic determinants of metabolically unhealthy obesity

Honors and Leadership:

• Endowed Frederick G.L. Huetwell Professorship
• Associate Director, Michigan MSTP Program
• Center Memberships: Samuel and Jean Frankel Cardiovascular Center, Caswell Diabetes Institute

Collaborations and Resources: The Lumeng Laboratory employs team-science approaches integrating bioinformatics, surgery, and translational biology. Current projects utilize single-nuclear RNA sequencing to map adipose tissue cellular diversity in obesity. Research is funded by NIH, American Diabetes Association, and institutional grants.