Jiandie Lin

Jiandie Lin is the Bradley M Patten Collegiate Professor in the Life Sciences at the University of Michigan. He serves as a Professor of Cell and Developmental Biology in the Medical School and as a Research Professor affiliated with the Life Sciences Institute.

His research focuses on metabolic regulation, particularly on:

• Developmental and disease-driven reprogramming of tissue metabolism
• Genetic/epigenetic mechanisms in metabolic control
• Interorgan communication through secreted metabolic factors
• Role of macrophage heterogeneity in liver disease

Notable scientific achievements include:

• Bradley M Patten Collegiate Professorship
• Leading breakthroughs in understanding lipid droplet dynamics and inflammatory signaling
• Elucidating TGF-beta and TREM2 pathways in metabolic liver disease

Recent work highlights: systemic metabolic crosstalk, cold exposure effects on fat metabolism, and paracrine signaling in NASH treatment. His laboratory actively investigates interorgan communication networks and liver microenvironment remodeling in metabolic disease and cancer.