Laurent Dejean

Laurent Dejean is an Associate Professor in the Department of Chemistry and Biochemistry at California State University, Fresno. He joined the faculty in 2011 and holds a Ph.D. in Biochemistry and Cell Biology from the University of Bordeaux 2, France. His postdoctoral research included work at the University of Barcelona and New York University.

Education:

• Ph.D., Biochemistry and Cell Biology, University of Bordeaux 2, France

Research Interests:

• Investigates mitochondrial regulation of apoptosis, focusing on Bcl-2 family proteins (Bax, Bak, Bcl-2, Bcl-xL).
• Examines how Bcl-2/xL proteins influence mitochondrial permeabilization and their role in cancer cell resistance to apoptosis.
• Studies cross-regulation of cell signaling and metabolic pathways, particularly metabolic shifts in tumor cells.
• Explores mitochondrial homeostasis, biogenesis, and their interplay with cell growth and death pathways.

Advising/Grants: No specific grants or advising details provided in text.

Labs/Teams: Lead a laboratory investigating Bcl-2/xL-Bax interactions and their therapeutic implications in cancer.