Knut Müller-Caspary

Prof. Knut Müller-Caspary is a faculty member at the Faculty of Chemistry and Pharmacy of Ludwig Maximilian University of Munich (LMU), leading a research group dedicated to advancing transmission electron microscopy (TEM) methodologies. His work bridges chemistry, physics, and structural biology through atomic-scale analysis.

His research encompasses:

• Structural characterization of solid-state specimens at subatomic resolution
• Chemical mapping via electron diffraction and spectroscopy
• Low-dose imaging of soft biological matter
• Electric field and potential measurements at picometer scales
• Development of 4D-STEM, electron ptychography, and AI-driven analysis techniques

Key recognition includes:

• ERC Synergy Grant (2023) for the 6-year 4D-BioSTEM project developing cryogenic TEM methodologies for protein/cell imaging

The group operates cutting-edge facilities including an aberration-corrected FEI Titan Themis 60-300 (S)TEM and FIB/SEM systems. It maintains strategic collaborations with Forschungszentrum Jülich, EPFL Lausanne, TUM, and Munich's interdisciplinary research network. Current work focuses on multidimensional data acquisition, quantum-scale electrical property mapping, and in-situ characterization under thermal/electrical stimuli.