Kathleen Collins

Kathleen Collins is a Professor in the Department of Internal Medicine - Infectious Diseases at the University of Michigan. Her research focuses on HIV pathogenesis, immune evasion mechanisms, and latent infection dynamics. She has published extensively on viral protein interactions with host immune systems, particularly Nef, Vpr, and Tat proteins.

• University of Michigan - Internal Medicine - Infectious Diseases

Research Interests:

• HIV immune evasion via Nef/Vpr/Tat proteins
• Latency mechanisms in T cells and macrophages
• Major histocompatibility complex (MHC-I) trafficking
• Epigenetic regulation of viral reservoirs
• Antiviral drug development targeting immune clearance

Scientific Trends: Recent work emphasizes multi-omic approaches to HIV latency, viral protein adaptation in macrophages, and lysosomal acidification pathways. Older publications cover hematopoietic stem cell infection, DNA replication mechanisms, and interleukin-1 gene regulation.