Karin Leiderman

Karin Leiderman, PhD, is an Associate Professor in the Department of Mathematics and a member of the UNC Lineberger Comprehensive Cancer Center. She also holds appointments in the Department of Biochemistry and Biophysics and the Computational Medicine Program at the University of North Carolina at Chapel Hill.

Her research integrates mathematical modeling, computational simulations, and experimental approaches to study biochemical and biophysical mechanisms in blood coagulation, clot formation, and bleeding disorders with applications in hemophilia and cancer-associated thrombosis. She leads the Leiderman Research Group, which develops open-source software frameworks like clotFoam for simulating thrombus formation under flow.

Recent publications highlight her work on:

• Mathematical analysis of anticoagulant drugs (emicizumab, concizumab) and their impact on coagulation
• Computational modeling of lipid surface enzyme kinetics and HIV-1 Env protein binding
• Development of multiscale models for hemostasis and thrombosis

Scientific awards include:

• NSF CAREER Award (2020)
• Colorado School of Mines Faculty Excellence Award (2021)
• W.M. Keck Graduate Student Mentorship Award (2020)
• Invited State-of-the-Art Speaker at ISTH (2022)

Dr. Leiderman has mentored numerous graduate and undergraduate students, including Jamie Madrigal (PhD, UNC), Kenji Miyazawa (PhD, UNC), and Nicholas Danes (PhD, Colorado School of Mines). Her research is supported by NIH R01 funding and focuses on contextualizing findings across mathematical and biological communities.