Jörg Höhfeld

Prof. Jörg Höhfeld is a Professor in the Department of Cell Biology at the University of Bonn. He serves on the Steering Committee of the Transdisciplinary Research Area (TRA) 'Life and Health', focusing on life sciences and healthcare research. His primary affiliation is with the Institut für Zellbiologie, where he leads studies on cellular stress responses and proteome integrity.

Education and Research Interests: His work centers on molecular mechanisms of proteostasis, including how chaperones prevent protein aggregation and regulate degradation pathways under stress. Key areas include the role of ubiquitin ligases like CHIP in aging and insulin signaling, and the role of chaperone-assisted selective autophagy (CASA) in muscle maintenance and mechanotransduction.

Grants and Advising: While specific grants are not detailed here, his research has resulted in significant publications (e.g., in Cell, Current Biology). No student advisees are listed in the provided text.

Labs and Teams: His research is conducted within the University of Bonn’s Institute for Cell Biology, collaborating with networks in transdisciplinary health-related research.