Juliet Lee

Juliet Lee is an Associate Professor in the Department of Molecular and Cell Biology at the University of Connecticut, specializing in Cell and Developmental Biology. Her research investigates the integration of molecular mechanisms and biomechanical properties in cellular movement.

• Ph.D., University of London (1986)

Lee’s work focuses on the mechano-chemical regulation of cell motility, emphasizing actin cytoskeleton dynamics, adhesion formation, and calcium signaling. She uses fish epithelial keratocytes as a model system due to their rapid movement, employing fluorescence microscopy, calcium imaging, and force detection assays.

Her publications span topics like traction force analysis, HSP27 roles in stress response, and mathematical modeling of motility. The research highlights collaboration with experts like Hightower and Knecht, with applications in aging, cancer biology, and mechanobiology.

Lee’s lab (https://jlee.lab.uconn.edu/) maintains a focus on interdisciplinary methods to bridge molecular events with whole-cell behavior, emphasizing force generation and signal transduction pathways.