معرفی
John Lukesh is an Associate Professor in the Department of Chemistry at Wake Forest University, Winston-Salem, NC. His research at the intersection of synthetic organic chemistry and biology focuses on designing redox-active molecules with therapeutic potential.
- Ph.D., University of Wisconsin–Madison (2014), under Ronald T. Raines
- Postdoctoral work, The Scripps Research Institute (2014–2017), with Dale L. Boger
Research Interests: The Lukesh lab develops novel redox-active molecules, emphasizing their applications in chemical biology and medicine. Key areas include:
- Chemical Biology: Probing reactive sulfur/selenium species in biological systems
- Medicinal Chemistry: Selenium-containing scaffolds for redox-based therapeutics
- Synthetic Methodology: Organoselenium reagents for heterocyclic synthesis via C–C bond formation
Publications highlight his work on hydrogen sulfide (H2S) and hydrogen selenide (H2Se) donors, ROS-responsive probes, and selenium-mediated synthetic methods. His awards include:
- NSF CAREER Award (2022–2027)
- NIH NIGMS MIRA (2024–2029)
- F. M. Kirby Family Faculty Fellowship (2022–2025)
- Wake Forest Award for Excellence in Research (2025)
His lab website (lukeshjc.sites.wfu.edu) details ongoing projects in redox chemistry and biological applications.
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