Johannes C. Hellmuth

Dr. Johannes C. Hellmuth leads the DKTK Junior Clinical Cooperation Unit for Non-Coding Cancer Biology at the Ludwig Maximilian University of Munich (LMU Klinikum), affiliated with the Department of Pathology under the School of Medicine. His research focuses on exploiting vulnerabilities in the non-coding genome of cancer cells, particularly through super-enhancer analysis and CRISPRi screening.

Research Interests:

• Functional interrogation of the non-coding genome
• Super-enhancer proteomes in oncogenesis
• Transcriptional condensates as therapeutic targets
• Non-invasive super-enhancer diagnostics

Publication Trends: Recent work spans epigenetic regulation in lymphomas, super-enhancer dependencies in cancer, and chromatin dynamics during immune cell differentiation, with a focus on integrating omics data for personalized therapies.