معرفی
Joseph M. Miano, PhD, is a Professor at the Medical College of Georgia, Augusta University, where he holds the J. Harold Harrison, MD, Distinguished University Endowed Chair in Vascular Biology. He is a core faculty member of the Vascular Biology Center and serves in the Department of Medicine, Cardiology division. His academic appointment is firmly rooted in vascular and cardiovascular research, with a strong emphasis on molecular mechanisms in vascular smooth muscle cells.
- BS in Biology and Exercise Science, SUNY Cortland, 1986
- PhD in Experimental Pathology, New York Medical College, 1992
- Postdoctoral Training in Molecular Biology, UT MD Anderson Cancer Center, 1995
Dr. Miano's research focuses on the transcriptional and post-transcriptional regulation of gene expression in vascular biology. His primary interests include CRISPR and prime editing in rodents, smooth muscle cell differentiation, regulation of human ACE2 in mice, development of advanced mouse and rat models, and the function of coding and noncoding genes in vivo. His lab is known for generating innovative gene-edited rodent models to explore vascular smooth muscle pathobiology.
His recent publications (2022–2024) highlight a strong trend in understanding long noncoding RNAs (lncRNAs) in vascular inflammation, CRISPR-based transgene mapping, and the role of the SRF-Myocardin switch in vascular disease. His work frequently appears in high-impact journals such as Circulation, Nature Cardiovascular Research, and Arteriosclerosis, Thrombosis, and Vascular Biology, reflecting sustained scholarly output and influence in cardiovascular science.
- J. Harold Harrison, MD, Distinguished University Endowed Chair in Vascular Biology
Dr. Miano mentors graduate students and postdoctoral fellows, teaching courses such as VBIO 9300 (Research in Vascular Biology), VBIO 8020 (New Frontiers in Vascular Biology), and PHRM 8042 (Pharmacology & Therapeutics I). He has not listed specific grants in the provided text, but his extensive publication record and endowed chair suggest significant research funding. His laboratory, located in CL-3072, is an active hub for vascular biology research, contributing to the mission of the Vascular Biology Center at Augusta University.
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