معرفی
Dr. Joann Diray Arce is an Assistant Professor at Harvard Medical School and a faculty member in the Precision Vaccines Program at Boston Children’s Hospital. She leads the Data Management and Analysis Core (DMAC), supporting large-scale, multi-institutional research in systems immunology and vaccine development. Her work is central to several NIH-funded initiatives and international consortia focused on understanding immune responses to vaccines and infections.
Her research focuses on systems immunology, integrating multi-omic data—genomics, transcriptomics, metabolomics, and immunophenotyping—to characterize immune responses in early life and during infectious diseases. Key areas include neonatal immunity, BCG and other vaccine responses, metabolic changes during infection, and the development of computational and cloud-based tools for data management in clinical research. She has pioneered resources like the Immune Data Resource, a curated compendium of systems vaccinology datasets from over 50 cohorts.
Dr. Arce’s recent publications reveal a strong trend in longitudinal multi-omic profiling of immune responses in COVID-19, vaccine responsiveness, and neonatal immunity. Her work frequently appears in top-tier journals such as Nature Immunology, Science Translational Medicine, and Cell Reports, demonstrating expertise in network modeling, biomarker discovery, and immune-metabolic interactions.
She leads a team of data scientists supporting the IMPACC study and other large consortia, contributing to data coordination, quality assurance, and advanced analytics. Her work bridges computational science and immunology, advancing the field of precision vaccines.
