Jian Fu

Jian Fu is a Professor in the Department of Toxicology and Cancer Biology at the University of Kentucky. He holds a Ph.D. from the University of Alabama at Birmingham (2001). His research focuses on inflammation and innate immunity mechanisms in critical care medicine, particularly lung, kidney, and vascular inflammation. He investigates epigenetic regulation of lung inflammation and carcinogenesis influenced by environmental factors, as well as nanotoxicology and nanoparticle drug delivery systems.

• Education: Ph.D., University of Alabama at Birmingham, 2001

His work addresses key areas like HDAC6 inhibition in acute lung injury, p53 regulation in fibrosis, and the role of urokinase-fibrinolytic systems in lung injury. His studies bridge molecular mechanisms with translational applications in critical care and toxicology.

Research trends in his publications emphasize cytokine pathways (e.g., TNF-α, LPS), epigenetic modifiers (HDAC6, Sirt1), and nanoparticle-based drug delivery systems. His work often employs murine models to investigate sepsis, fibrosis, and injury responses.

No awards or student advisees are listed. His research is conducted within the Department of Toxicology and Cancer Biology at UK.