معرفی
Jessica Nouws, PhD, is an Associate Research Scientist in Pulmonary, Critical Care & Sleep Medicine at Yale School of Medicine. She holds an EMBO fellowship and specializes in metabolic disorders, mitochondrial biology, and pulmonary fibrosis. Her research integrates molecular biology, genetics, and clinical studies to address obesity-related metabolic pathologies.
Education:
- PhD in Pediatrics, Radboud University Nijmegen Medical Center (2013)
- Short-term fellowship in Aging & Health, Newcastle University (2012)
- MSc from Wageningen University (2008)
Research Interests:
Dr. Nouws focuses on mechanisms linking mitochondrial dysfunction to lung disease, metabolic disorders (e.g., insulin resistance), and obesity. She investigates genetic variants influencing NAFLD and explores stem cell-driven lung repair mechanisms. Her work bridges basic science and clinical applications, particularly in pediatric and adolescent populations.
Publications:
Her recent work addresses IPF pathogenesis via proteostasis signaling, mitochondrial regulation in emphysema, and ECM dynamics in obesity-related insulin resistance. Earlier contributions include landmark studies on ACAD9’s role in complex I biogenesis and genetic drivers of metabolic phenotypes.
Awards:
- EMBO fellow
Collaborations:
Dr. Nouws collaborates with clinicians and researchers such as Maor Sauler (pulmonary fibrosis), Nicola Santoro (metabolic genetics), and Alla Vash-Margita (obesity studies). Her interdisciplinary team spans Yale’s Pulmonary Division and metabolic disease programs.
Labs/Teams:
Her research is embedded within Yale’s Pulmonary, Critical Care & Sleep Medicine Department, leveraging institutional resources in translational medicine and metabolic research.