معرفی
Jeffrey Toth, PhD, FAIMBE, serves as Adjunct Professor in the Department of Orthopaedic Surgery at the Medical College of Wisconsin (MCW), with dual adjunct appointments at Marquette University in the School of Dentistry (Biomaterials) and College of Engineering (Biomedical Engineering). He directs the Walter F. Joyce Jr. Memorial Biomaterials Laboratory at Marquette University and is a core faculty member of the Orthopaedic Rehabilitation and Engineering Center (OREC), a joint MCW-Marquette initiative advancing orthopaedic device innovation.
His research spans biomaterials development, tissue engineering, and spinal implant analysis, focusing on bone graft substitutes, osteoinductive protein delivery systems, and retrieval studies of explanted devices. Dr. Toth pioneered the seminal tissue engineering definition adopted globally and demonstrated that host responses to spinal implants vary by biomaterial composition—a critical insight for device safety. Current projects address spine impairment (the leading cause of activity limitation in US adults), with emphasis on radiolucent fusion devices and PEEK polymer applications.
Dr. Toth's work is supported by NIH (NIAMS/NIDRR), National Arthritis Foundation, American College of Surgeons, and industry partnerships. His laboratory employs advanced techniques including undecalcified histology, microradiography, and quantitative histomorphometry for pre-clinical biomaterials testing.
- Fellow of the American Institute for Medical and Biological Engineering (AIMBE), 2010
- Outstanding Graduate School Educator, MCW Graduate School of Biomedical Sciences, 2017
As an educator, Dr. Toth supervises graduate students through OREC and teaches biomaterials courses, integrating retrieval analysis findings into translational research training. His lab maintains active collaborations with spine device manufacturers and international research groups, with outcomes directly informing clinical implant design and surgical protocols.
