معرفی
Jarrod Johnson is an Assistant Professor in the Department of Microbiology and Immunology at the University of Utah. His research focuses on innate immunity mechanisms against viral pathogens, particularly HIV-1, through three key levels: pathogen detection, signaling regulation, and host response dynamics. He utilizes CRISPR screening, molecular virology, and systems biology tools to address critical questions in virology and immunology.
- Education: B.S. from University of Florida, Ph.D. from University of North Carolina at Chapel Hill
- Research Areas: HIV molecular virology, virus-host interactions, innate antiviral defenses, gene regulation in myeloid cells
- Techniques: CRISPR screening, primary human myeloid cell genetic modification, -omics data integration, advanced imaging
Johnson's lab investigates how HIV-1 evades innate immune detection and how transcriptional regulation maintains immune homeostasis. Recent work highlights the role of viral capsids in immune evasion and host factors like ILF3 in modulating inflammatory responses.
Key trends in his publications include:
- HIV-1 capsid interactions with innate sensors
- Transcriptional regulators of dendritic cell maturation
- CRISPR-based identification of host factors in malaria and HIV
- Mechanisms of mitochondrial transfer in cancer and immunity
- Epigenetic remodeling during viral infections
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