معرفی
Jan Vijg is a Professor in the Department of Genetics and Department of Ophthalmology & Visual Sciences at Albert Einstein College of Medicine, and currently serves as Chair of the Department of Genetics. He holds the Lola and Saul Kramer Chair in Molecular Genetics. His research focuses on genome instability as a driver of aging and age-related diseases, combining transgenic animal models, next-generation sequencing, and single-cell genomics to study mutations and epimutations in aging organisms. His work has advanced understanding of somatic mutations in human tissues, epigenetic heterogeneity, and the biological limits of human lifespan.
Dr. Vijg's projects include NIH-funded research and collaborations on genome maintenance pathways, cancer, and longevity assurance systems. His lab develops cutting-edge methods for analyzing single-cell genomic and epigenomic data, with applications to liver, lung, and immune cells. His team has published influential studies on somatic mutation profiles, DNA repair mechanisms, and the implications of genomic mosaicism in aging and disease.
Key findings include demonstrating age-related increases in genomic instability and identifying a potential biological ceiling for human lifespan. Dr. Vijg advises multiple graduate students and postdoctoral fellows, mentoring researchers in genetics, bioinformatics, and aging biology.
