Ingolf M Bach

Ingolf Bach is a Professor at the UMass Chan Medical School, affiliated with multiple departments including Molecular, Cell and Cancer Biology, NeuroNexus Institute, and Program in Molecular Medicine. His research focuses on LIM domain proteins and their associated cofactors, such as RLIM/Rnf12 and CLIM/Ldb, which play critical roles in cell fate specification, X chromosome inactivation, and mammary gland development.

Education:

• University of Konstanz, Germany: BA in Biology, MA in Molecular Biology
• Paris Diderot University, France: PhD in Biotechnology

Research Interests: Dr. Bach investigates how protein complexes regulate gene expression during development and disease. Key areas include X chromosome inactivation in female mice, neuronal differentiation, and breast cancer mechanisms. His lab employs molecular, biochemical, and genetic approaches using mouse models.

Publications: His recent work spans Xist gene regulation, germ cell specification, and metabolic control via RLIM, with studies in journals like Nature, Cell, and EMBO J. Keywords include Molecular Biology, Genetics, and Developmental Biology.

Advising and Collaborations: Dr. Bach mentors students in PhD rotation projects and offers postdoctoral positions. He collaborates with institutions such as the Pasteur Institute and University of Hamburg.

Labs and Teams: His laboratory at UMass Chan explores X chromosome inactivation, neuronal development, and mammary gland biology, utilizing mouse genetics and biochemical techniques.