Hui Chen

Hui Chen is an Assistant Professor in the Department of Biological Sciences at the University of South Carolina within the McCausland College of Arts and Sciences. The research focuses on understanding how cellular components orchestrate embryo development at the earliest stages, particularly the regulation of the early embryonic genome for spatiotemporal cell fate specification and novel mechanisms of biological size regulation in development and diseases.

• University: University of South Carolina
• College: McCausland College of Arts and Sciences
• Department: Biological Sciences
• Academic Rank: Assistant Professor

Research Interests span Developmental Biology, Embryonic Genome Regulation, and Biological Size Control. Key areas include elucidating spatiotemporal patterning of zygotic genome activation, studying nuclear size regulation, and investigating how cellular dimensions integrate with differentiation. These studies utilize interdisciplinary technologies and have implications for developmental disorders and cancer.

Publications highlight work on transcriptional dynamics in early embryogenesis, nuclear scaling mechanisms, and cancer cell migration. Articles are published in journals such as Current Biology, Developmental Cell, and bioRxiv, with a focus on developmental gene regulation and biomechanical constraints.

Labs & Teams: The Chen Lab leverages model embryonic systems and cutting-edge technologies to explore fundamental principles of early development, aiming to inform strategies for addressing developmental disorders and cancer.