Hexin Chen

Hexin Chen is a Professor in the Department of Biological Sciences at the University of South Carolina, McCausland College of Arts and Sciences. His research focuses on cancer biology, cellular stress, and microbiome-immune interactions.

• Investigates mechanisms of breast cancer recurrence through targeting cancer stem cells (CSCs)
• Develops immunotherapies for breast cancer by studying IL-1α-driven immunosuppression
• Explores gut microbiome modulation to enhance cancer treatment outcomes

Using multi-omics, nanotechnology, and transgenic models, his work spans:

• Signaling pathway dysregulation in CSCs
• Immune checkpoint resistance mechanisms
• Microbiome metabolite-host crosstalk

His publications (2024-2022) highlight advances in kinase inhibition, microRNA therapy, and microbial sulfonolipids for cancer and inflammatory diseases. Collaborations include interdisciplinary teams in nanomedicine and mathematical modeling.