Amanda A. Amodeo

Amanda A. Amodeo serves as Assistant Professor of Biological Sciences at Dartmouth College and is affiliated with the Molecular and Cellular Biology Graduate Program.

Education:

• B.S., University of Wisconsin - Madison
• Ph.D., Stanford University

Her research program investigates fundamental mechanisms of cell size control in developmental contexts, with primary focus on Drosophila embryogenesis where conventional cell size regulation is inverted. The lab employs quantitative imaging, genetics, genomics, molecular biology, and mathematical modeling to dissect molecular pathways coordinating cell cycle progression, transcription, and chromatin dynamics through nuclear-to-cytoplasmic ratio sensing. Current work emphasizes histone regulation, zygotic genome activation, and cell cycle remodeling during embryonic transitions.

Analysis of publications spanning 2015-2024 reveals consistent exploration of nuclear-cytoplasmic scaling principles across model systems, with recent breakthroughs in chaperone-mediated histone incorporation and real-time tissue imaging techniques. The work bridges molecular mechanisms with systems-level understanding of developmental timing.

Scientific Awards: No scientific awards were mentioned in the provided materials.

Dr. Amodeo actively recruits PhD rotation students and post-doctoral scholars for her research program, emphasizing interdisciplinary approaches to developmental biology questions.

The Amodeo lab operates within Dartmouth's Biology Department using Drosophila embryo and oocyte systems, with laboratory facilities located in the Life Sciences Center. Research integrates wet-lab experimentation with computational modeling to address size-sensing mechanisms in development.