معرفی
Hongyi Xu is a researcher and principal investigator at the Department of Chemistry, Stockholm University, specializing in electron crystallography for structure determination of materials and biomolecules. He completed his PhD in Materials Engineering at the University of Queensland (2013) with the Dean’s Award for Research Excellence and John Simmons Prize for Best Thesis, followed by a postdoc at SU (2014–2016) under Prof. Xiaodong Zou.
- Education
- BEng (Hons) in Mechatronics, University of Queensland (2009)
- PhD in Materials Engineering, University of Queensland (2013)
- Current Role
- Principal Investigator, Stockholm University (2018–Now)
- Lecturer for Electron Crystallography (2022–Now)
- Guest Lecturer for Bioanalytical Chemistry and Experimental Chemistry Methods (2020–Now)
Research Focus: Development of MicroED and 3D electron diffraction methods for solving structures of submicron/nanocrystals from proteins to pharmaceuticals. Key projects include:
- Charge state analysis in metalloenzymes
- Fragment-based drug design via high-throughput MicroED
- Multidimensional toolkit for modern electron microscopy
- Cryo-EM applications (SPA, cryo-ET, MicroED)
Scientific Contributions: Solved over 180 novel structures (2018–2023) using MicroED, including first protein structures and protein-inhibitor binding studies. Collaborated with 25+ international groups to establish 3D ED facilities.
Scientific Awards:
- Wenner-Gren Postdoc Fellowship (2014–2016)
- Young Scientist Lecturer Award (2019)
- Consultant, IUCr Commission on Electron Crystallography (2021–Now)
Grants: Secured 6 competitive projects totaling ~SEK 18.6M, including a Swedish Research Council Starting Grant (2018–2021) and European Commission NanED ITN (2021–2025).
Supervision: Mentored 1 postdoc (main), 3 postdocs (co), 2 PhD students (main), and 4 PhD students (co) at SU. Alumni include researchers at UCLA, Karolinska Institute, and Rosalind Franklin Institute.
