Holly Janes

Holly Janes, PhD is Professor and Head of the Biostatistics, Bioinformatics and Epidemiology Program within the Vaccine and Infectious Disease Division at Fred Hutchinson Cancer Center. She also holds appointments as Professor in the Public Health Sciences Division and Member of the Translational Data Science Integrated Research Center (TDS IRC).

Her research focuses on statistical design and analysis of vaccine efficacy trials, with specialization in HIV prevention and vaccine science. Key interests include:

• Statistical methods for biomarker evaluation
• Pediatric vaccine trials
• Human challenge studies
• Risk prediction modeling
• Treatment decision optimization

Dr. Janes leads the Statistical Data Management Center for the HIV Vaccine Trials Network and develops methodologies for HIV prevention efficacy trials. Her work directly informs vaccine development strategies and clinical trial frameworks.

As an Affiliate Professor and Graduate Faculty member in Biostatistics at the University of Washington, she maintains strong academic collaborations. Her educational background includes:

• PhD in Biostatistics, University of Washington (2005)
• MS in Mathematics, University of Massachusetts (2000)
• BA in Philosophy of Physical Science and Mathematical Modeling, Skidmore College (1998)