Holger Bastians

Holger Bastians is Professor of Cellular Oncology at University Medical Center Göttingen, leading research on chromosomal instability in cancer. His group discovered abnormal microtubule dynamics as a key trigger for aneuploidy in cancer cells.

Research examines cross-talk between DNA replication stress and mitotic dysfunction using molecular oncology approaches. Current projects investigate BRCA1 regulation of mitotic spindle assembly and Wnt signaling in chromosome segregation. Heads DFG Research Unit on chromosome instability mechanisms.