Henrique Bittencourt

Henrique Bittencourt serves as an Associate Clinical Professor in the Department of Pediatrics at the University of Montreal's Faculty of Medicine. Based at CHU Sainte-Justine in Montreal, he holds critical leadership roles including Co-Director of the Myeloid Neoplasia Program, Director of the Recurrent Acute Leukemia Program, and Co-Medical Manager of the Early Research Unit in Hemato-Oncology.

His academic credentials include:

• Medical degree from Universidade Federal do Rio Grande do Sul, Brazil (1990)
• Internal medicine/hematology residency at Hospital de Clinicas de Porto Alegre (1996)
• Bone marrow transplantation fellowship at Saint-Louis Hospital, Paris
• Ph.D. in Health Sciences from Universidade Federal do Rio Grande do Sul (2002)

Dr. Bittencourt's research centers on hematopoietic stem cell transplantation and leukemia immunotherapy, with specialized focus on cord blood transplants, GVHD/GVL dynamics, and CAR-T cell development. His work bridges clinical practice and translational research through phase I/II hemato-oncology trials targeting refractory leukemias.

Recent publications (2018-2019) demonstrate concentrated expertise in CAR-T therapeutics for B-cell acute lymphoblastic leukemia, examining tisagenlecleucel efficacy, resistance mechanisms, and quality-of-life outcomes. Earlier work established foundational knowledge in CD34+ cell dosing for bone marrow transplantation.

He actively leads specialized clinical teams at Sainte-Justine, directing the Myeloid Neoplasia Program and Recurrent Acute Leukemia Program while co-managing early-phase research initiatives that advance pediatric hemato-oncology care.