معرفی
Sajad J. Khazal serves as Associate Professor in the Department of Medicine at Loma Linda University School of Medicine, specializing in Hematology/Oncology with clinical expertise in stem cell transplantation and management of hematologic malignancies across pediatric and adult populations. His work addresses critical complications including veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) and genetic bone marrow failure syndromes.
Research interests prioritize Hematology, Oncology, and Stem Cell Transplantation, with deep specialization in Leukemia subtypes, Pediatric Hematology/Oncology, and VOD/SOS pathophysiology. Current investigations focus on risk stratification for transplant complications, novel targeted therapies like menin inhibitors for acute leukemias, and genetic mechanisms underlying bone marrow failure disorders.
Recent publications (2024-2025) demonstrate concentrated scholarly output in VOD/SOS epidemiology across age groups, innovative treatment protocols for core-binding factor AML, and international collaborative frameworks for pediatric leukemia therapeutics. Key thematic threads include genetic mutation profiling, age-specific risk factor analysis, and integration of antibody-drug conjugates like gemtuzumab into transplant conditioning regimens.
As active investigator across 25+ ongoing clinical trials, Dr. Khazal leads Children's Oncology Group protocols spanning acute lymphoblastic leukemia (AALL1631, AALL1131), acute myeloid leukemia (AAML1531), neuroblastoma (ANBL0032), and solid tumors, while contributing to industry-sponsored cellular therapy trials (Poseida Therapeutics) and National Marrow Donor Program registries. His grant portfolio emphasizes optimizing transplantation safety, reducing treatment-related mortality, and validating novel biomarkers for early complication detection.
