Hisham M. Abdel-Azim

Hisham M. Abdel-Azim, MD, MS is a Professor at the School of Medicine with appointments in three divisions: Pediatrics (Hematology/Oncology Division), Medicine, and Basic Sciences (Biochemistry Division) at New York Medical College. His work focuses on pediatric hematopoietic cell transplantation, leukemia research, and cellular therapy development.

Dr. Abdel-Azim's research interests span multiple areas of pediatric hematology and oncology:

• Pediatric Hematopoietic Cell Transplantation and Cellular Therapy
• Leukemia Biology and Treatment Strategies
• Stem Cell Transplantation Complications and Management
• Novel Immunotherapies for Pediatric Cancers
• Genomic and Molecular Mechanisms in Hematologic Malignancies
• Transplant-Related Toxicities and Late Effects

His recent publications (2024-2025) demonstrate a strong focus on improving outcomes in pediatric hematopoietic cell transplantation, with particular emphasis on managing complications like veno-occlusive disease, optimizing conditioning regimens, and developing novel cellular therapies. His work spans from basic science investigations of molecular mechanisms in leukemia to large multi-center clinical trials through the Children's Oncology Group and other consortia. A significant portion of his research addresses the unique challenges of treating pediatric patients with hematologic malignancies, with publications covering acute lymphoblastic leukemia, acute myeloid leukemia, and severe combined immunodeficiency.

Dr. Abdel-Azim serves as Principal Investigator for numerous research projects funded by prestigious organizations including the National Cancer Institute, Children's Oncology Group, National Marrow Donor Program, and industry partners. His work often involves multi-center collaborations across the United States and internationally.

He serves as a key investigator in multiple clinical trials focused on:

• Novel cellular therapies for relapsed/refractory leukemias
• Optimizing conditioning regimens for hematopoietic cell transplantation
• Understanding and preventing transplant complications
• Genomic mechanisms of treatment resistance
• International registry studies for cellular therapy outcomes