معرفی
Hayley M. McDaid is an Associate Professor in three departments at Albert Einstein College of Medicine: Oncology (Medical Oncology), Medicine (Oncology & Hematology), and Molecular Pharmacology. Her research focuses on molecular mechanisms of cancer therapy resistance, particularly in lung and breast cancers, with a senescence-centric approach. She investigates therapy-induced senescence (TIS) as a driver of drug resistance and tumor dormancy, and develops strategies to target senescent cells (senolytics) and enhance tubulin ligand efficacy.
Her lab’s key projects include: biomarker development for TIS detection, genomic instability in senescent cells, and optimizing discodermolide-based therapies via structural refinement. Collaborations include work with Dr. Amos B. Smith III (UPenn) on tubulin ligand chemistry.
Publications span 2010–2022, covering topics like 4E-BP1-dependent resistance, panobinostat as a senolytic, and nanoparticle-encapsulated doxorubicin. No awards are listed here, though her work contributes to translational oncology advancements.
