Guido Hermey

Dr. Guido Hermey is a Research Professor at the University Medical Center Hamburg-Eppendorf (UKE), where he leads research at the Institute of Molecular Neurogenetics. His work focuses on molecular mechanisms underlying neuronal plasticity and neurodegeneration, employing multidisciplinary approaches including advanced imaging, biochemistry, and bioinformatics.

His research examines:

• Activity-dependent changes in neuronal gene expression and protein trafficking
• Role of Vps10p-domain receptors in endosomal transport and synaptic plasticity
• Molecular pathways linking lysosomal dysfunction to neurodegenerative disorders
• Disease mechanisms in Alzheimer's, Batten disease, and autism spectrum disorders

Hermey's recent publications demonstrate a strong focus on lysosomal storage disorders and synaptic function, with consistent research output exploring neurodegenerative disease mechanisms through molecular and cellular neuroscience approaches. His work frequently investigates protein trafficking pathways and their disruption in disease states.

He leads a multidisciplinary research team studying neuronal plasticity using techniques including:

• Transcriptional profiling of neuronal activity
• Live-cell imaging of protein trafficking
• Characterization of disease-linked proteins
• Bioinformatic analysis of neuronal gene expression