Sean T. Sweeney

Sean T. Sweeney is a Senior Lecturer at the University of York. His research spans synaptic membrane trafficking, neurodegeneration, and mitochondrial signaling, with a focus on lysosomal storage disorders and synaptic dysfunction in diseases like frontotemporal dementia.

His work utilizes Drosophila models to investigate lipid metabolic perturbations, reactive oxygen species (ROS) regulation, and endosomal trafficking defects linked to hereditary neuropathies and sensory decline. Recent publications emphasize neurodegenerative disease mechanisms and cellular quiescence regulation.

Key collaborations include researchers at institutions such as the University of Massachusetts and CNRS. His publications highlight interdisciplinary approaches bridging molecular genetics, physiology, and cell biology in neurodegenerative and metabolic disorders.