معرفی
Professor Glenn Burley holds the position of Professor of Chemical Biology at the University of Strathclyde's Department of Pure and Applied Chemistry (Faculty of Science). His research focuses on molecular probes for gene expression regulation, synthetic organic chemistry, and bio-orthogonal chemistries for drug delivery. He completed a Bachelor of Medicinal Chemistry (Hon. I) and PhD in Organic Chemistry from the University of Wollongong, Australia. Postdoctoral training included roles at the University of Sussex (2001–2003) and as an Alexander von Humboldt Fellow at the University of Munich (2004–2006). He became an independent researcher as an EPSRC Advanced Fellow at the University of Leicester (2007) before joining Strathclyde in 2011.
- Education:
- Bachelor of Medicinal Chemistry (Hon. I), University of Wollongong
- PhD in Organic Chemistry, University of Wollongong
- Professional Activities:
- Speaker at LINXS Chemistry of Life Meeting (2024)
- Invited speaker at Bürgenstock Conference on Stereochemistry (2024)
- Advisor to Cpi Innovation Services Limited (2023–present)
Research interests include exploring regulatory mechanisms of transcription and RNA processing via synthetic organic chemistry and biocatalysis. A key focus is developing bio-orthogonal chemistries for cell-selective drug delivery, particularly oligonucleotide therapies. The Burley Group (www.burleylabs.co.uk) emphasizes problem-driven approaches. Recent projects include TargoPep (therapeutic oligonucleotide delivery), Gene Solutions Extension, and high-throughput PROTAC synthesis targeting epigenetic synthetic lethality.
Professional contributions include leadership in major grants (e.g., EPSRC, BBSRC), with roles as Principal Investigator for projects like the £1.5M TargoPep initiative. His work aligns with UN Sustainable Development Goals, particularly in advancing affordable and clean energy through chemical innovation.
Lab facilities include advanced analytical equipment such as Agilent HPLC and automated purification systems, enabling high-throughput synthesis and biological evaluation of novel compounds.
