Gitte Hoffmann Bruun

Gitte Hoffmann Bruun is a researcher at the Department of Biochemistry and Molecular Biology, University of Southern Denmark, specializing in translational biology. Her work bridges genetic research and molecular medicine, focusing on RNA splicing mechanisms and genetic susceptibility to diseases.

• Research Interests: Biochemistry, Genetics, Molecular Biology, RNA Splicing, Exome Sequencing, and Genetic Susceptibility.

Bruun's research leverages advanced bioinformatics and molecular biology techniques, such as deep learning models for predicting protein-RNA binding effects and exome sequencing to identify disease-related genes. Her work has applications in developing allele-specific therapies and antisense oligonucleotide-based treatments.

Her publications and patents highlight a strong emphasis on splice switching oligonucleotides, pseudoexon targeting, and Mycobacterial infection genetics. These contributions underscore her role in translational research linking computational biology to clinical applications.