Maja Dembic

Maja Dembic is an Associate Professor at the Department of Clinical Research, University of Southern Denmark, with affiliations at Odense University Hospital (OUH) and Karolinska Institutet (KI). Her primary research unit is the Research unit of Clinical Genetics in Odense, where she focuses on genetic and molecular mechanisms of disease. She maintains an active ORCID profile (0000-0003-2505-6863) and can be contacted via mdembic@health.sdu.dk.

Her research centers on genetic disorders including propionic acidemia and phenylketonuria, cardiovascular genetics, and molecular therapeutics. She employs advanced genomic techniques such as exome sequencing and splice-switching antisense oligonucleotides to investigate enzyme dysfunction, somatic mutations, and pathological mechanisms in atherosclerosis and aneurysm formation. Key methodologies include pseudoexon modulation, candidate gene analysis, and next-generation sequencing platforms.

Analysis of her recent publications (2024-2025) reveals a dual research trajectory: cardiovascular genetics focusing on somatic mutations in aortic diseases, and metabolic disorder therapeutics targeting enzyme rescue through RNA splicing correction. Her work bridges fundamental molecular biology with clinical applications, particularly in developing oligonucleotide-based interventions for inborn errors of metabolism.

Dr. Dembic operates within the Research unit of Clinical Genetics at Odense, participating in extensive international collaborations evident from her multicenter studies across European institutions. Her research network spans cardiovascular screening initiatives, atherosclerosis mutation mapping, and therapeutic development for rare genetic disorders.