Thomas Koed Doktor

Thomas Koed Doktor is a Senior Research Associate in the Department of Biochemistry and Molecular Biology at the University of Southern Denmark, with extensive expertise in RNA splicing mechanisms and molecular genetics. His research bridges fundamental molecular biology with translational applications for genetic disorders.

Dr. Doktor holds a PhD and MSc in Molecular Biology, providing him with deep expertise in genetic and molecular research techniques. His educational background forms the foundation for his current work in splicing mechanisms and therapeutic development.

His primary research focuses on exon biology, RNA splicing mechanisms, and therapeutic approaches for genetic disorders. Doktor investigates how exonic mutations affect splicing patterns and develops oligonucleotide-based therapies to correct aberrant splicing in conditions such as propionic acidemia and amyotrophic lateral sclerosis (ALS). His work with casein kinase 2 (CK2) explores connections between protein kinases and metabolic disorders, cancer, and obesity.

Doktor's recent publication portfolio demonstrates a strong trajectory in RNA biology with increasing clinical relevance. His work spans from fundamental splicing mechanisms to therapeutic applications, with a growing emphasis on metabolic disorders through his CK2 research. The integration of molecular genetics with therapeutic development represents the central theme across his diverse publication record.

• Nominated for researcher prize (2014)

Doktor has served as head coordinator for multiple significant research projects including Lundbeckfonden's initiative on correcting aberrant splicing for ALS treatment and Muskelsvindfonden's research on splicing errors in ALS. His grant portfolio demonstrates strong support from Danish funding bodies for investigations into splicing mechanisms and their therapeutic applications for genetic disorders.

His research involves collaboration with international teams across molecular biology, genetics, and clinical research domains. Doktor's work in translational biology focuses on bridging molecular discoveries with potential clinical applications, particularly in developing oligonucleotide therapies for genetic disorders and exploring metabolic pathways relevant to obesity and cancer.