معرفی
Gary E. Gibson is a tenured Professor of Neuroscience at Weill Cornell Medicine, where he serves as Lab Director at the Laboratory for Mitochondrial Biology and Metabolic Dysfunction in Neurodegeneration. He also holds the position of Associate Director at the Dementia Research Service within the Burke Neurological Institute. His academic career spans institutions including UCLA (where he completed postdoctoral work and faculty appointments) and Cornell University, where he earned his Ph.D.
- Education:
- B.S. in Zoology and Chemistry, University of Wyoming
- Ph.D. in Physiology (Biochemistry/Neuroscience), Cornell University
Research Focus: Dr. Gibson's work centers on mitochondrial dysfunction and oxidative stress in neurodegenerative diseases (Alzheimer's, Huntington's, Parkinson's). His lab investigates:
- Mechanisms of α-ketoglutarate dehydrogenase complex (KGDHC) deficiency
- Metabolism-calcium signaling interactions
- Protein post-translational modifications (succinylation, acetylation)
- Thiamine-dependent metabolic pathways
- Translational studies using induced pluripotent stem cells
- Clinical trials testing metabolic interventions (e.g., benfotiamine)
Publications reveal expertise in:
- TCA cycle enzyme abnormalities
- Neurodegenerative biomarker discovery
- Calcium dyshomeostasis
- Metabolic-epigenetic crosstalk
- Neuroprotective strategies
- Animal models of oxidative stress
Honors:
- ASN Award for Outstanding Young Investigator
- Three U.S. patents
- NIH Director’s Talk and other honorary lectureships
Grants: Continuously funded by NIH/NIA grants (P01AG014930) for mitochondrial dysfunction research since 1999. Serves on Alzheimer’s Association and American Federation for Aging Research review panels.
