معرفی
Fulan Guan is an Associate Research Scientist in Pharmacology at Yale School of Medicine, Yale University. He holds a PhD from Guangzhou University of Traditional Chinese Medicine (2002). His primary affiliation is the Department of Pharmacology, with additional roles in related research areas.
Research interests focus on herbal medicine mechanisms, particularly PHY906 and YIV compounds, in cancer therapy, immunology, and drug development. Key areas include anti-tumor efficacy enhancement, immune modulation in hepatocellular carcinoma, and quality control of herbal products. He also explores traditional Chinese medicine applications in conditions like tinnitus and alopecia, leveraging metabolomics and imaging techniques.
Publications highlight interdisciplinary work in oncology, immunology, and pharmacology, emphasizing herbal medicine's role in modern therapeutics. Collaborations include studies on PHY906's effects on tumor microenvironments and its synergy with chemotherapy agents like irinotecan. Notable projects involve developing novel agents like YIV-818-A targeting prostate cancer and elucidating mechanisms for reducing chemotherapy side effects.
His research bridges traditional Chinese medicinal practices with contemporary biomedical approaches, contributing to drug development and translational medicine. Active collaborations span pharmacology, microbiology, and clinical oncology, reflecting a commitment to interdisciplinary science.
