معرفی
Frank C. Ko, PhD is an Assistant Professor in the Department of Anatomy & Cell Biology at Rush Medical College, Rush University, with secondary appointments in the Department of Orthopaedic Surgery. His research focuses on molecular mechanisms of intramembranous bone regeneration and musculoskeletal homeostasis, particularly examining periostin-expressing cells and circadian rhythm interactions with bone metabolism.
- PhD in Musculoskeletal Biomechanics from Cornell University
- Postdoctoral training at Massachusetts General Hospital and Beth Israel Deaconess Medical Center
Research spans bone regeneration, implant fixation, and disease models (osteoporosis, osteoarthritis, sarcopenia). Key projects include:
- Periostin cell lineage tracing in marrow ablation recovery
- Wnt/β-catenin activation for accelerated healing
- Phosphate-mTORC1-BMAT interactions
- Gut-bone axis through colonic circadian disruption
- Translational preterm pig skeletal modeling
Current funding includes NIH R01 and R21 grants. Scientific accolades feature the Searle Innovator Award. His lab collaborates with orthopedic surgeons and computational biomechanists to develop novel therapeutic strategies for musculoskeletal repair and implant integration.
