معرفی
D. Rick Sumner, PhD, serves as Professor and Chair of the Department of Anatomy & Cell Biology at Rush Medical College, Rush University, and directs the Rush MicroCT and Histology Core. With over 30 years of continuous research funding from major institutions including NIH, DoD, NASA, and industry partners, his work has established him as a leading researcher in bone biology and orthopedic biomechanics. His laboratory maintains active collaborations with research groups both within Rush and internationally.
Dr. Sumner's research focuses on fundamental aspects of bone biology with direct clinical applications. His primary areas of investigation include bone regeneration mechanisms, orthopedic implant fixation, and the role of bone in osteoarthritis pathogenesis. Specific projects examine the genetics of bone regeneration, effects of premature birth on postnatal bone development, early detection of particle-induced peri-implant osteolysis, and cartilage-bone interactions in osteoarthritis. His lab employs advanced imaging techniques including micro-computed tomography, backscatter scanning electron microscopy, and Fourier transform infrared spectroscopy, complemented by histology, mechanical testing, and biomarker analysis.
Analysis of Dr. Sumner's recent publications reveals a strong interdisciplinary approach spanning bone biology, immunology, microbiome research, and circadian rhythms. His work demonstrates how bone health intersects with systemic conditions including inflammatory bowel disease, circadian disruption, and premature birth. The research consistently applies sophisticated imaging and analytical techniques to understand bone-implant interfaces and develop improved diagnostic and therapeutic approaches for orthopedic conditions.
Dr. Sumner serves as Principal Investigator or Multiple Principal Investigator on multiple NIH grants including R01AR080118 (bisphosphonates and bone matrix), R01AR079179 (systems genetics of bone regeneration), R21HD102026 (bone health in formerly premature individuals), and P30AR079206 (Chicago Center on Musculoskeletal Pain). He has mentored numerous postdoctoral fellows including Frank Ko, PhD, and Brittany M. Wilson, PhD, who continue research in bone regeneration and implant osteolysis.
Dr. Sumner's laboratory operates as the Laboratory of D. Rick Sumner within the Department of Anatomy & Cell Biology at Rush University Medical Center. The lab maintains the Rush MicroCT and Histology Core, providing advanced imaging capabilities for bone and implant research. His team includes bioinformaticians, postdoctoral researchers, and technical staff working collaboratively on multiple projects related to bone regeneration, implant fixation, and osteoarthritis mechanisms.
