Francesca Bernassola

Francesca Bernassola is an Associate Professor of Molecular Biology at the University of Rome Tor Vergata, focusing on the role of E3 ubiquitin ligases in cancer pathogenesis, particularly WWP1 in acute myeloid leukemia.

Research Focus: Her work investigates:

• Regulation of p53 family proteins (p63/p73)
• Ubiquitin-dependent pathways in cancer
• WWP1-mediated leukemogenesis
• Cancer stem cell biology
• Chemotherapy resistance mechanisms

Her laboratory employs ubiquitin remnant profiling and preclinical models to identify therapeutic targets.

Research has demonstrated WWP1's essential role in AML cell proliferation and survival, with inhibition strategies showing promising results.