معرفی
Etienne Leveille is a Research Fellow in the Department of Hematology and Medical Oncology at the Yale School of Medicine, affiliated with the Center of Molecular and Cellular Oncology. He completed his MD at McGill University with research on Parkinson's disease genetics and lymphoma pathogenesis. His current work focuses on ferroptosis mechanisms in B-cell malignancies, particularly diffuse large B-cell lymphoma (DLBCL), under the mentorship of Dr. Markus Müschen. Key research interests include oncogenic signaling inhibition, metabolic vulnerabilities, and novel therapeutic approaches in hematologic cancers.
Educational background: MD from McGill University (2021). Research training includes studies on hereditary spastic paraplegia genetics and apoptosis mechanisms in lymphoma. He has contributed to over 20 peer-reviewed publications, with recent work addressing CAR T-cell toxicity biomarkers and clonal hematopoiesis-cardiomyopathy links in cancer patients.
He holds the 2025 Lymphoma Research Foundation Postdoctoral Fellowship Grant for his project on ferroptosis induction in DLBCL. Collaborations include work with Dr. Markus Müschen's lab and interdisciplinary teams at Yale Cancer Center. His research combines optogenetic tools, computational biology, and preclinical models to advance targeted therapies.
Key publications highlight discoveries in metabolic reprogramming of lymphomas, proteomic profiling of CAR T-cell toxicities, and synthetic lethality strategies leveraging NAD+ biosynthesis pathways. Current projects aim to translate ferroptosis mechanisms into clinical therapies for treatment-resistant B-cell malignancies.