معرفی
Jaewoong Lee is an Assistant Professor Adjunct in the Department of Medical Oncology and Hematology at Yale School of Medicine. His research focuses on discovering molecular targets to treat B-cell malignancies, leveraging genetic engineered mouse models to study B-cell development, BCR-mediated immune responses, and leukemogenesis. He holds affiliations with the Müschen Lab and is part of the Cancer Signaling Networks and Center of Molecular and Cellular Oncology.
Education: PhD (2012), MSc (2009), and BSc (2007) from Kyungpook National University.
Research interests include oncogenic signaling pathways, metabolic vulnerabilities in cancer, and therapeutic strategies for B-cell leukemias/lymphomas. Key collaborators include Markus Müschen, Kadriye Nehir Cosgun, and Kohei Kume.
Notable research highlights include identifying β-catenin degradation vulnerabilities, CD25-mediated feedback control of oncogenic kinases, and repurposing GSK3B inhibitors for lymphoid malignancies. Current work explores lipid metabolism and optogenetic modulation of oncogenic signals.
Laboratory affiliations: Müschen Lab (300 George Street, New Haven, CT).
