Eiron Cudaback

Eiron Cudaback serves as an Associate Professor in DePaul University's College of Science and Health, teaching core courses including Integrated Human Anatomy and Physiology, Molecular Mechanisms of Human Disease, and Introduction to Pharmacology as a full-time faculty member.

His academic credentials include:

• PhD in Health Sciences and Neuroscience

Dr. Cudaback's research centers on neurodegenerative diseases with emphasis on APOE-driven neuroinflammation. His laboratory investigates how APOE ε4—the strongest genetic Alzheimer's risk factor—dysregulates microglial and astrocyte function, employing biochemical, in vitro, and in vivo approaches to uncover molecular pathways in Alzheimer's, Parkinson's, MS, and TBI. Key focus areas include chemokine signaling, neuroimmune crosstalk, and genetic modulation of disease progression.

Analysis of his 2014-2021 publications reveals consistent exploration of APOE genotype effects on neuroinflammatory mechanisms, spanning from molecular studies of glial chemokine production to behavioral outcomes in transgenic models. His work demonstrates translational connections between genetic risk factors, innate immune responses, and neuropathology across multiple neurodegenerative conditions.

No student advising details or research grants were specified in available materials.

He leads an active research laboratory utilizing multidisciplinary techniques to dissect neuroinflammatory pathways in neurodegeneration, with collaborations examining microglial depletion effects, APOE-neprilysin interactions, and dopamine-neurodegeneration relationships in disease models.