معرفی
Wenjie Luo is a researcher at the Brain and Mind Research Institute, Weill Cornell Medical College, focusing on neurodegenerative diseases and neuroimmunology. His role involves investigating molecular pathways linking tauopathy, microglial function, and genetic risk factors for Alzheimer's disease.
- Education: B.S. and M.S. from Peking University (China), Ph.D. from Albert Einstein College of Medicine (2001)
His research explores the interplay between neuroinflammatory mechanisms, tau pathology, and genetic variants in Alzheimer's disease progression. Key areas include the cGAS-STING pathway, TREM2 agonism, and microglial interactions with oligodendrocytes.
Recent publications highlight his work on tau propagation models, microglial signaling pathways (NF-κB, AKT), and sex-based differences in neurodegeneration. He collaborates on grants from the National Institute on Aging and BrightFocus Foundation, focusing on tau metabolism, TREM2 ligands, and APOE mutations in neurodegenerative diseases.
