معرفی
Edward C. Twomey is an Assistant Professor in the Department of Biophysics and Biophysical Chemistry at the Johns Hopkins School of Medicine. His research focuses on the structural and molecular mechanisms of ion channels and cell-cell junctions in the nervous system, particularly glutamate receptors and the blood-brain barrier. He employs cryo-electron microscopy (cryo-EM) and electrophysiology to study these systems.
- Key affiliations: Neuroscience Training Program, XDBio Training Program, BCMB Training Program, Program in Molecular Biophysics
His lab develops novel techniques like the C-SPAM platform for time-resolved cryo-EM. Recent work includes discovering memantine's dual inhibition of AMPA and NMDA receptors, with implications for Alzheimer's treatment. He advises students like Calli Bonin and collaborates with labs at UT Health Houston.
Awards: None explicitly listed in the provided text.
Grants and funding: Not detailed here, but research involves method development and therapeutic insights.
