معرفی
Douglas C. Lobner is a Professor in the Department of Biomedical Sciences at Marquette University, affiliated with the College of Health Sciences. He holds roles such as Associate Chair and serves on multiple institutional committees, including the Institutional Animal Care and Use Committee. His research focuses on environmental toxins (e.g., mercury, BMAA) and their role in neurodegenerative diseases like Alzheimer’s, Parkinson’s, and ALS. A second focus is dental materials’ toxicity and pulp capping efficacy, emphasizing system xc- regulation.
Education:
- B.S. in Biomedical Engineering, Marquette University (1980-1984)
- M.S. in Biomedical Engineering, University of Wisconsin-Madison (1984-1986)
- Ph.D. in Physiology, University of Wisconsin-Madison (1986-1991)
- Postdoctoral Fellow, Neurology, Washington University School of Medicine (1991-1997)
Research Interests: Investigates environmental toxin interactions with genetic predisposition in neurodegeneration. Key projects include BMAA’s role in ALS, mercury toxicity mechanisms, and growth factor effects in dental pulp cells. Uses cell culture models to study system xc- as a neurotoxicity mediator.
Grants & Funding: Secured grants from NIH (NIA, NIDCR, NIDA), Michael J. Fox Foundation, and Promentis Pharmaceuticals, totaling over $3.5M. Topics include system xc- targeting for Parkinson’s, schizophrenia, and ALS.
Advising & Service: Advised over 15 graduate students and 40 undergraduates. Served on curriculum committees for dental and biomedical sciences programs. Organized research presentations and judged poster competitions.
Labs & Collaborations: Member of the Integrative Neuroscience Research Center (INRC) and collaborates with institutions like Ajou University (South Korea) and Promentis Pharmaceuticals.
