Dorothea Schulte

Dorothea Schulte is a Professor at Goethe University Frankfurt, affiliated with the Neurological Institute (Edinger Institute) within the university's Neuroscience Center. Her research focuses on molecular mechanisms governing neural stem- and progenitor cell fate, with a particular emphasis on TALE-HD transcription factors.

• University: Goethe University Frankfurt
• Department: Neurological Institute (Edinger Institute)
• Email: d.schulte@em.uni-frankfurt.de

Her work explores how TALE-HD proteins balance proliferation and differentiation of neural progenitors, regulate chromatin dynamics, and interact with extracellular signaling pathways. Research spans developmental biology, cancer biology, and bioinformatics applications in neuroscience.

Publications highlight her expertise in transcriptional regulation, miRNA in neural stem cell control, and the dual roles of TALE-HD factors in neuroblastoma. Key methodologies include genetically modified mouse models, retroviral gene transfer, and nuclear protein purification.