Dorothea Fiedler

Prof. Dr. Dorothea Fiedler is the Head of the Fiedler Group and Managing Director at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin, Germany. Her research is situated within the Research Section of Chemical Biology, where she leads a multidisciplinary team investigating the role of inositol polyphosphates and pyrophosphates in cellular signaling and metabolism.

Her research interests lie at the intersection of chemistry and biology, focusing on understanding how phosphate-based molecules regulate cell homeostasis and how their dysregulation contributes to diseases such as cancer, diabetes, and obesity. She employs techniques from organic chemistry, chemical genetics, proteomics, and cell biology to develop novel tools like activity-based probes and biosensors for studying these signaling networks.

Although specific recent publications are not listed in the provided text, her group's work consistently centers on the signaling-metabolism interface, particularly protein pyrophosphorylation and the functional annotation of inositol phosphates, reflecting a strong trend in chemical biology and molecular pharmacology.

• Scientific Awards: None listed in the provided text.

Prof. Fiedler has mentored numerous PhD students and postdoctoral researchers, many of whom have gone on to complete their degrees under her supervision. Her group actively recruits new PhD candidates and postdocs, indicating ongoing research projects and likely grant funding, although specific grants are not mentioned. She previously held an academic position at Princeton University before relocating her lab to FMP in Berlin.

The Fiedler Group is embedded within the FMP’s Chemical Biology research section and collaborates with core facilities such as Mass Spectrometry, NMR, Screening Unit, Peptide Chemistry, and Cryo-EM, enabling a comprehensive and technologically advanced research environment.