معرفی
Prof. Dr. Henning Jacob Jessen holds the Chair of Bioorganic Chemistry at the University of Freiburg's Institute of Organic Chemistry. His research integrates chemistry and biology to investigate cellular phosphate conjugates, including inositol pyrophosphates, magic spot nucleotides, and condensed phosphates.
Research focuses on developing chemical tools for biological studies, metabolic pathway analysis, and therapeutic applications. Key areas include enzymatic synthesis of phosphate derivatives, metabolic flux analysis, structural biology of phosphate transporters, and inhibitor design for kinases.
Recent publications demonstrate innovation in:
- Advanced LC-MS methods for metabolite profiling
- Chemoenzymatic synthesis of inositol derivatives
- Structural mechanisms of phosphate transporters
- Mathematical modeling of metabolic flux
- Development of kinase inhibitors with therapeutic potential
He leads a large research group with multiple postdoctoral researchers and PhD students investigating phosphate biochemistry across biological systems.
